As usual, there are several ways you could register your TIFF images, as long as you have the registration/projection information as data somewhere. Obviously, if each needs registering based on, say, grid lines on the map, then you're probably stuck with manual registration. Do you have your registration information in a file or database, or perhaps are they GEOTIFFs?
TAB files, with the same file name body, carry the registration information so it's possible to script (in MapBasic or Python) so code to write the TAB for each TIF. If all your TIFFs are in the same projection, you can manually register one to get a model TAB file and programmatically output variations of it.
Alternatives without programming include FME which is very good at converting rasters, as is the underlying GDAL library and tools. Both can read pretty much anything and output TAB+TIF pairs.
Hope that helps.
Europa Technologies Ltd.