I am not familiar with the Simba Athena ODBC driver. However, if you have configured the Athena DSN then you can use the DB Query node to access the service.
It would be necessary to configure any DB options via the DSN/ driver configuration as the DB Query node does not offer the capability to set options.
If this is not possible you may want to consider using the Athena JDBC driver in conjunction with the JDBC Query node. The JDBC Query node allows you to specify DB options using key=value pairs within the DbOptions property or within the JDBC connection string, as required.