Hi Laise,
I would always recommend applying updates as they generally include bug fixes, so installing the latest version is the best way to stay bug-free!
If you are already using the 64 bit version of the Routefinder tool (5.0 onwards), then no special treatment is required. If you were moving from 32 bit (version 4 and earlier), then you would need to be sure to update your speed file (.spd) and ensure you have your turn restriction data in delimited text format. I recommend checking with your data supplier that your road network data is compatible with both 32 bit and 64 bit versions of Routefinder.
Hope that answers your question!