Assure has layouts that can be "database layouts", which means can connect to via jdbc and run sql queries. So, Hive can do sql queries that map-reduce over hadoop/hdfs data, and technically possible to use with Assure as just another jdbc driver and layout rule. We don't think ZooKeeper does anything like jdbc/sql. Hive may be configured to use ZooKeeper to find out what services and "stuff" are out there.
It is possible for Assure to add "plugin layouts" that access other types of data; these are technically outside of the product proper.
Its not clear to what you might want to obtain via ZooKeeper that we might expose as a kind of plugin layout. Whenever we start down this track, though, things usually end up in DQ+ instead.